Harold Frost
Harold M. Frost (1921 – 19 June 2004) was an US-American orthopedist and surgeon considered to be one of the most important researchers and theorists in the field of bone biology and bone medicine of his time.[1][2][3] He published nearly 500 peer-reviewed scientific and clinical articles and 16 Books and is according to the Science Citation Index one of the most cited investigators in skeletal research.[1]
His main academic inputs included[1]:
- Development of Bone Histomorphometry for description of cellular based bone formation and Bone resorption processes
- the eleventh rip Biopsy used for diagnosis of metabolic Bone diseases
- Research on the multi-cellular unit as a key to bone metabolism
- the experimental proof that Estrogen reduces bone formation
- the histological proof of micro-damages in human bone biopsies
- the basic model of the adaptation of the Growth plate to mechanical stress
- the Utah-Paradigm of Bone physiology (Mechanostat-Theorem), an enhancement of Wolff's law stating that Bone adapts to mechanical stress and that hence there is a close link between muscle and bone
Books by Harold M. Frost
- Bone remodelling dynamics, The Henry Ford Hospital surgical monographs, Thomas (Springfield, Ill.), 1963
- The laws of bone structure, The Henry Ford Hospital surgical monographs, Thomas (Springfield, Ill.), 1964
- Mathematical Elements of Lamellar Bone Remodelling, The Henry Ford Hospital surgical monographs, Thomas (Springfield, Ill.), 1964
- Bone biodynamics, Henry Ford Hospital international symposium, [14], Little, Brown (Boston) 1964
- The bone dynamics in osteoporosis and osteomalacia, The Henry Ford Hospital surgical monographs, Thomas (Springfield, Ill.), 1966
- An introduction to biomechanics, Surgical monographs, Thomas (Springfield, Ill.), 1967, 0398028249
- Orthopaedic surgery in spasticity (Orthopaedic lectures Vol. 1), Thomas (Springfield, Ill.), 1972
- The physiology of cartilaginous, fibrous, and bony tissue (Orthopaedic lectures Vol. 2), Thomas (Springfield, Ill.), 1972, ISBN 0398025622
- Bone remodeling and its relationship to metabolic bone diseases (Orthopaedic lectures Vol. 3), Thomas (Springfield, Ill.), 1973, ISBN 0398025886
- Bone modeling and skeletal modeling errors (Orthopaedic lectures Vol. 4), Thomas (Springfield, Ill.), 1973, ISBN 039802667X
- Orthopaedic Biomechanics (Orthopaedic Lectures Vol. 5), Thomas (Springfield, Ill.), 1973, ISBN 0398028249
- Symposium on the Osteoporoses Part 1: Physioplogy, Pathophysiology, and Diagnosis, Saunders (Philadelphia), 1981
- Symposium on the Osteoporoses Part 2: Therapy and Prevention, Saunders (Philadelphia), 1981
- Intermediary organization of the skeleton, CRC Press (Boca Raton, Fla), 1986, ISBN 0849359481
- Bone in clinical orthopedics - Chapter 14: Determinants of bone strength and mass: a summary and clinical implications by Geoff Sumner-Smith, Georg Thieme Verlag, 2002, ISBN 0865778299, [1]
- The Utah Paradigm of Skeletal Physiology Vol. 1, ISMNI
- The Utah Paradigm of Skeletal Physiology Vol. 2, ISMNI
References
- ^ a b c Turner C, Burr D, Jee WS, Smith S, Recker RR, Axelrod DW, Takahashi HE, Villanueva AR, High WB, Martin RB, Parfitt AM: Tribute to Harold M. Frost M.D., J Musculoskel Neuron Interact 2004; 4(4):348-356, PMID 15758257
- ^ Recker RR: In Memoriam: Harold M. Frost, M.D., Dr.Sc. Hon., orthopedist, Bone. 2004 Sep;35(3):581, PMID 15729783
- ^ Jee WS: Harold M. Frost, M.D., D.Sc. (hon) - one man's association, J Musculoskelet Neuronal Interact. 2006 Apr-Jun;6(2):113-21, PMID 16849819
External links
- Tribute to Harold Frost in Journal of Musculoskeletal Neuronal Interactions, 4(4), 2004, 348-356
- Harold M. Frost, M.D., D.Sc. (hon) – One man’s association in Journal of Musculoskeletal Neuronal Interactions, 6(2), 2006
- Harold M Frost William F. Neuman Awardee 2001 in Journal of Musculoskeletal Neuronal Interactions, 2(2), 2001, 117-119
- ASBMR Harold M. Frost Young Investigator Award
- ISMNI - International Society of Musculoskeletal and Neuronal Interactions
- Sun Valley Workshops - IBMS Annual Sun Valley Workshops
| Persondata |
| Name |
Frost, Harold |
| Alternative names |
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| Short description |
American orthopedist and surgeon |
| Date of birth |
1921 |
| Place of birth |
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| Date of death |
19 June 2004 |
| Place of death |
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